A Tablet Hardness Tester checks the mechanical integrity of tablets. The hardness is closely linked to disintegration and dissolution characteristics.
Manual Tablet Hardness Testers
Manual testers require the operator to place each tablet individually and initiate the test.
Advantages:
- Lower initial cost
- Simple operation
- No power requirements for some models
- Suitable for low-volume testing
Limitations:
- Time-consuming for large batches
- Subject to operator variability
- Limited data recording capabilities
Automatic Tablet Hardness Testers
Automatic testers feature motorized operation and can test multiple tablets with minimal operator intervention.
Advantages:
- High throughput
- Reduced operator fatigue
- Consistent testing conditions
- Integrated data logging and statistics
- 21 CFR Part 11 compliance options
Features of Modern Automatic Testers:
- Auto-loading mechanisms
- Multi-parameter testing (hardness, thickness, diameter)
- Statistical analysis (mean, SD, min/max)
- Printer and computer connectivity
Load Cell Technology
Both manual and automatic testers now commonly use load cell technology, which:
- Provides precise and repeatable measurements
- Reduces variability in quality control
- Requires less frequent calibration than mechanical systems
- Converts mechanical force to electrical signals for digital display
Choosing the Right Tester
Consider:
- Testing volume requirements
- Budget constraints
- Data integrity needs
- Regulatory compliance requirements