Choosing the right dissolution testing equipment is critical for pharmaceutical laboratories. This guide compares different systems to help make informed decisions.
Manual Dissolution Testers
Characteristics
- Basic paddle or basket assemblies
- Manual sampling and analysis
- Lower initial investment
Best For
- Small-scale operations
- Research and development
- Training purposes
Semi-Automated Systems
Characteristics
- Automated sampling with manual analysis
- Programmable sampling times
- Moderate investment level
Best For
- Medium-throughput laboratories
- Routine quality control
- Facilities transitioning to automation
Fully Automated Systems
Characteristics
- Automated sampling and analysis
- Integrated UV or HPLC detection
- Real-time data collection
- Highest investment but lowest per-test cost
Best For
- High-volume production facilities
- 24/7 operations
- Facilities requiring maximum throughput
Key Selection Criteria
Throughput Requirements
Consider daily sample volume and turnaround time requirements when selecting equipment capacity.
Regulatory Requirements
Ensure equipment meets applicable pharmacopeial standards and offers required documentation capabilities.
Budget Considerations
Factor in not just initial cost but ongoing consumables, maintenance, and operator time.
Future Scalability
Select systems that can grow with your laboratory needs through modular expansion options.
Integration Capabilities
Modern dissolution testers offer various integration options:
- LIMS connectivity
- Barcode sample tracking
- Electronic batch records
- Cloud data storage